List of Painkillers

painkiller tablets

Pain is an undesirable sensation that might end up being discomforting at greater strengths. The typical websites or origin of pain are back, eye, face, stomach, joint pain, tongue etc. The triggered pain can be of different types like severe, moderate or even moderate. Several types of pain killers are readily available in the market to obtain rid of the pain. Pain killers are offered in pharmacy either as over-the-counter drugs however some may need prescription from a medical doctor. Below is the list of common pain relievers, both over-the-counter and prescribed, along with their effects, potency and adverse effects.

List of Painkillers with Reviews

General Guideline

  • Pain killers which are NSAIDs (nonsteroidal anti-inflammatory drugs) works on the patho-physiological processes that elicit pain, fever and other signs of swelling in the body.
  • Corticosteroids pain reliever are usually given for the management of musculoskeletal injuries due to its effect on shutting down inflammation causing processes.
  • The pain which is set off by any damaged or sensitive nerves (see most commonly in cases like sciatica or shingles) is generally handled by nerve blockers or anti-depressants. These tablets have the capacity to regulate the understanding of pain by main worried system.
  • Some pain- killers are made use of as muscle relaxants to decreases the intensity of pain triggered by the muscles group. This pain reliever serve as sedative for main worried system.
  • Factor behind consuming medication is to enhance the lifestyle. It is essential to recognize that every pain reliever is connected with some negative effects in short term or long term. Therefore it is encouraged to learn and determine potential drawbacks prior to taking in any painkiller.

Following are the description of a few of the pain reliever:


It is among the popular pain killers readily available (primarily utilized for the management of common headaches and non nerve discomforts). The efficient dosage is 2 tablets which can be consumed a minimum of 4 times a day (or at every 6 hrs interval). This dose and dosing routine is thought about safe for grownups. There are no common adverse effects for this medication and this drug can be used for longer time period. Nevertheless overdose of paracetamol can trigger some serious negative effects; for that reason it is highly recommended not to increase the dosage if the intensity of pain increases. If pain symptoms cannot resolve within 3 days, get in touch with the basic physician.


This drug is a type of NSAIDs i.e. non steroidal anti inflammatory drugs. It works best on inflammation triggering drugs in a very same method it is used for dealing with arthritis or any injury. This drug is not enabled to be made use of for longer time periods unless the swelling does not vanish. If this drug is consumed for longer time periods, it can result in significant adverse effects like bleeding, indigestion, heart problems and kidney issues. It is highly encouraged not to take in overdose of this drug as it can trigger severe repercussions.


This drug does not work well alone but can provide far much better results when used with paracetamol in a single formulation. Over the counter drugs are available under the label of co-codamol (which is paracetamol integrated with lower amount of codeine). Greater potency of codeine should just be utilized on doctor’s prescription. Some other painkillers with greater potency consist of Zydol (tramadol) and dihydrocodeine.

Drugs under this category are considered as habit-forming or addicting. The factor behind is these drugs makes an individual feel unhealthy for a short time duration when stop taking in. If for any certain factor this drug is consumed for longer period then consult your basic doctor for suggestions.

Amitriptyline and Gabapentin

Gabapentin is the drug used for dealing with epilepsy and amitriptyline medication and is used for dealing with anxiety. Both of the drugs are also given to patients for dealing with pain activated by damaged or hyper-sensitive nerves that includes sciatica, shingles or nerve pain caused by diabetes. This medication is taken in when prescribed by the general doctor. Adverse effects of both the drugs consist of dizziness and drowsiness.


This drug is thought about as effective and best pain reliever offered. Some other drugs fall under this classification consist of fentanyl, buprenorphine and Oxycodone. It is encouraged to book using this pain killer just in severe pain. These medications are only consumed when recommended by pain professional or general physician as the doctor will keep an eye on the development on dosage potency. These drugs are typically used for long term to administer the pain.

Strong opioids are medicines used to deal with severe or long-lasting (persistent) pain. Although there are numerous kinds of strong opioids, morphine is the most frequently utilized strong opioid and usually the first one your doctor will prescribe, according

Oxymorphone hydrochloride extended-release tablets are suggested for the management of pain severe sufficient to require daily, ongoing, long-term opioid treatment and for which alternative treatment choices are insufficient.

The most typical side-effects are constipation, feeling sick (queasiness), and tiredness. It is uncommon for individuals who take a strong opioid to deal with pain to become addicted to strong opioids.

The following table lists more OTC and recommended painkillers:

List of Painkillers by strength (from strongest to weakest)

OTC Pain Killers
Brand Name
Generic Name
Per Pill Dose
Best Uses
Motrin 800
(effectively used as an antipyretic, and analgesic).
Classified under NSAIDs
220 mg
800 mg
Treat rheumatism, arthritis and musculo-skeletal issues
naproxen sodium
(one of the very potent and powerful anti-inflammatory agents)
220 mg
Prescribe mainly for the management of arthritis pain and inflammation. It is also effective for other
musculo-skeletal ailments
44 291 tablet
200 mg
Treat muscle aches and fever
Combination of acetaminophen and aspirin (NSAID)
325 mg
500 mg
Given for the acute management of headache
L374 caplet
500 mg
Treat fever, can be used instead of aspirin if a person is allergic to salicylates or aspirin, given to arthritis patients, treat rheumatism and musculo-skeletal issues
Aspirin (also classified under
NSAIDs or acetylsalicylic acid)
81 mg
325 mg
Helpful for the management of pains and minor aches

Prescription Pain Killers
Brand Name
Generic Name
Per Pill Dose
Best Uses
Problems Caused
Dilaudid (tabs)
1 mg
2 mg
3 mg
4 mg
Dilaudid is considered as more effective as compared to morphine with some serious side effects
Fentora Duragesic
Lollipop or Skin patch
The strength of fentanyl is the result of an estimate since it was not developed when study was conducted. It is a powerful substance for treating fragmentation and gunshot wounds. The overdosage is associated with serious side effects and consequences. It is highly recommended to handle fentanyl carefully as mishandling can lead to death due to respiratory depression.
5mg 7.5mg
10mg 15mg
20mg 30mg 40mg
Oxymorphone hydrochloride extended-release tablets are suggested for the management of pain severe sufficient to require daily, ongoing, long-term opioid treatment and for which alternative treatment choices are insufficient.
MS Contin RMS
15 mg
100 mg
It is considered as the 4th most powerful drug available.
Oxycontin 40
Oxycodone HCl
40 mg
Oxycodone is considered as powerful and very effective.
NOTE: The strength of oxycodone is an estimation as it does not exist when study was conducted
Acetaminophen and oxycodone HCl
2.5 mg to 650 mg
Aspirin, oxycodone, terephthalate oxycodone HCl
325 mg
4.50 mg
0.38 mg
Meperidine HCl
50 mg
100 mg
Opiates drug and synthetic opiates drugs are considered as the most powerful pain killers, but their use is abuse as all these drugs can make a person habitual of it.
Including large quantity of Tylenol (acetaminophen) with these drugs is prohibited for pharmaceutical companies and the reason behind is its overdose can totally destroys liver.
** The strength of Norco is an estimation as it does not exist while study was conducting.
Acetaminophen and hydrocodone
5 mg to
500 mg
Acetaminophen and hydrocodone
5 mg to
500 mg
Lorcet Plus
Acetaminophen and hydrocodone
7.5 mg to
650 mg
Vicodin ES
Acetaminophen and hydrocodone
7.5 mg to
750 mg
Acetaminophen and hydrocodone-APAP
5 mg to 325 mg
10 mg to 325 mg
Acetaminophen and hydrocodone
10 mg to 500 mg
Vicodin HP
Acetaminophen and hydrocodone
10 mg to 660 mg
50 mg
Gives relief from moderate pain
Constipation, nausea, dizziness, drowsiness, headache and vomiting
* NOTE: when the study is conducting Ultram and Celebrex does not exist. Their scores are an estimation
(COX-2 inhibitor)
100 mg
200 mg
Rheumatoid, osteoarthritis and other sources of acute pain in addition to menstruation pain
Moderately increase the risk of bleeding in stomach, stroke and
heart attack

Notify your health care expert about any previous history of substance abuse. All patients treated with opioids for pain require careful tracking by their healthcare specialists for signs of abuse and dependency, and to identify when these analgesics are not needed.


Updated: February 26, 2017 — 3:42 am

The Author

Reyus Mammadli

Healthy lifestyle advisor. Bachelor Degree of Medical Equipment and Electronics.

40 Comments on List of Painkillers

Add a Comment
  1. Obviously, one can’t always get every option onto a table like this but I believe that Oxymorphone is conspicuously missing.

    1. Angie Baumgartner

      Yes it is i wonder where it fits in because that’s what i take !

      1. Opana is oxymorphone !

    2. Thanks for reminder. Opana (Oxymorphone) was added to the list.

  2. I would say that Fentanyl is the strongest, with Opana as number 2, and Oxycodone as number 3.

    1. People mistakenly believe fentanyl to be the strongest but it is actually dilaudid.

      1. I would have to respectively disagree, as I have personal experience with everything on this list and can say with confidence that Paul is correct!

        1. I had intravenous Morphine, which wasn’t touching the pain, so the went to Dilaudid. Before the nurse was finished injecting I was floating away. Have never in my life had a pain med that hit that hard that fast.
          Of course it also made the room spin wildly for days and I had to be put back on fluids because the nausea was so severe.
          I had Fentanyl patches for back injury but I didn’t get enough pain relief so I took Tramadol too.

          1. The patches that you had to take it home tramadol are very strong if you do them in violation of their label. They can be eaten and that’s all I’m saying because I don’t want to be blamed for any deaths!

      2. Agreed. Personally I think fentanyl is not worth my time. Dilaudid actually works.

    2. Is Fentanyl made in pill form or only patches? My friend’s husband has terminal cancer and is in excruciating pain. When he was in the hospital he had a morphine drip but it didn’t seem to help much. They sent him home with hydrocodone (but gave them a hard time about it!) Next time in hospital he got dilaudid which did help. Hospice has given him methadone(?) and Fentanyl patches but he is still in pain. Seems like they would give a dying cancer patient the strongest thing there is whatever that is.

  3. what about Dolo 650

    1. It is Acetaminophen, which already mentioned in the list.

  4. What about acetaminophen with Codeine aka T-3

  5. how many of them are available in india?

  6. Where are the Sufenta, Etorphine, and then the king Carfentanil. im sure the basic compounds are listed but these drugs are at the top, they are deadly, not so much Sufenta but the other 2 are adn probably cannot be consumed by humans without dying.

  7. I had a bone infection. Morphine and oxcies were useless, doc put me on dilaulid. Wow that stuff is great. Dangerous if your not careful.

  8. This list is weakest to strongest and not strongest to weakest per the title.

    1. Thank you, Gregory. You are right. A will do correction in the tables.

  9. Where does methadone fit in this list

    1. We will check and add in future. Thank you.

    2. Methadone provides a decent euphoria and can also be enhance with other medications like Promethazine (antihistamine), Benzo’s, and marijuana. Despite what people say Methadone is not difficult to come off of physically. I was on it for 10 years and was taken off of it by decreasing my dose by 20% every 3 days. It wasn’t pleasant by any means but I heard horror stories about coming off of Methadone and it wasn’t the worst thing in the world. Take Care.

  10. I see codeine mentioned in the text, not the chart itself.

    1. I just had spinal fusion surgery and I was on the heaviest of pain meds. My doctor asked me to take a dose of each of Percocet, Injected Dilaudid, Opana, Fentanyl, and Oxycodone. In descending order, the strongest of what I took (it depends on how your brain reacts to the meds to relieve pain) I would say Dilaudid(injected), Opana(tabs), Fentanyl(tabs), Percocet(tabs), and finally Oxycodone(tabs). I have an extremely high tolerance to pills and unfortunately an extremely low tolerance to pain so really none of them really helped ME. But I based that list off of what lessened the pain the most. Our brains are all different and we all react to pills and pain differently. I just had my L4, L5, and S1 vertabraes fused together so you can imagine how bad that pain is (about 50 times worse than a compound fracture to me). Just try around and see what works for you, if you’re looking to get high off these… Percocet, Fentanyl(BE VERY CAREFUL WITH THIS!), and Dilaudid are the best. Keep away from high dosages and be careful because you can end up in very bad situations. AND DO NOT MIX WITH ALCOHOL UNDER ANY CIRCUMSTANCES, YOU WILL REGRET IT.

      1. Yo Marshall
        Just had the same fusion a month ago . U have a laminectomy also?

  11. is xanax considered an opioid

    1. No, Xanax is not a narcotic, it is a bezodiazepine. Please read more about xanax here:

  12. Thanks for putting this list out here. I had surgery for prolapsed hemorrhoids. Morphine via IV helped but did not completely relieve the pain. Dilaudid took care of the pain pretty fast!

    In the hospital, it was 2 Oxycodones, plus the dilauid every 4 to six hours. Pain free is a good feeling.

    Now I have a pinched nerve in my head that gives frequent and sometime severe ear aches. I take regular tylenol type meds in the day, and a bit of hydrocodone with some more tylenol type at night.

    So far, the spiking pains in the night haven’t disturbed my sleep more than once or twice in the 8 hours I try to sleep. I just hope I can manage the level of pain with low dose codeine and the tylenol. If I can sleep, I can tolerate the discomfort pretty good duing the day.

  13. This isnt veey accurate. Theres thr morphine side and condiene side. On the Morphine side it goes Morphine to Dihydromorphone (Dilaudid), to Oxymorphone (Opana)

  14. i had mulitple breaks and fractures the worse one was pelvic with dislocated hip, doctors not helping me at all, i am buy herion off the street. scared that i might get a bad batch, but i no other chioce. so annyoing the pain is, what can i do any suggestions, please and thanx

  15. Anyone who has to use the stronger ones certainly has my sympathy. Must be horrendous living with pain THAT bad..

  16. where does butalb-acetamin-caff 50-325-40 fall in the strongest to weakest chart

  17. sad states one should require painkillers which damages your liver/kidney..our bodies can naturally repel pain through simple breathing exercises without resorting to addictive drugs..

    1. Sorry Brian but exercises does not work for me have try not help there for me

    2. Sorry brian wondering if you have every suffrted with excruciating pain?.m

      1. I believe the last was an open wound surgery without local Anesthetic..I requested for it..the pain subsided as we gotten deeper into it..

        1. You are lucky but I would rather a lethal injection then then amount of pain this is causing me

    3. You are not everyone ! I am in a small group that does not like downers but I hate pain even more ! I had surgery on 8 hammertoes and the pain is close to unbearable for me .I hyperventilate when they were trying to remove the stitches ! The pain is horrific ! It took 3 visits and they do not even offer a topical coolant

  18. Dilaudid is defiantly the strongest I’ve had. the last 2 times I was in the hospital (one for a gastroparesis flare and one from being hit by a car) that’s what they gave me, tho I don’t like opiates at all, they make gastroparesis worse and don’t act well with dysautonomia so they make my blood pressure dangerously low. by anychance anyone know whats the strongest non-opiate pain med?

  19. The worst pain I ever had was detoxing.

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