Alternative for Synvisc Injection

Synvisc Introduction

Synvisc-One is just for injection into the knee, carried out by a doctor or other competent healthcare expert. Synvisc-One has not been evaluated to show pain relief in joints other than the knee. Tell your doctor if you dislike products from birds– such as feathers, eggs or poultry– or if your leg is swollen or infected.

Synvisc-One has actually not been tested in children (≤ 21years old), pregnant women or women who are nursing. You need to inform your doctor if you believe you are pregnant or if you are nursing a child.

Most Popular Alternatives for Synvisc Injection

Does PRP work better than SynVisc?

In this corner, the world’s most commonly used biologic injectable for knee arthritis-SynVisc. In the other corner, your own platelets, a.k.a. PRP. The winner? Well a study released recently may help decide that honor.

Platelet Rich Plasma (PRP) is now being used in patients with knee arthritis. However, there isn’t that much research yet published that reveals it operates in these patients.

A few studies showing that PRP has the tendency to work better in patients with more mild and early arthritis than in patients with more severe arthritis and that stem cells tended to work much better for patients with more severe arthritis. A more recent research study adds more fuel to this fire, this time comparing Hyaluronic acid (HA) (SynVisc, OrthoVisc, Hyalgan, Supartz, etc.) to PRP for knee arthritis patients. The research study involved 150 patients affected by both early and severe knee arthritis. Fifty symptomatic patients were treated with 3 PRP injections into the joint and two other groups of patients were treated with HA injections. One group was treated with injections of high-molecular weight HA (thicker HA like SynVisc); the other group was treated with low-molecular weight HA (thinner HA like Hyalgan).

Side Effects of Using Synvisc

Side Effects of Using Synvisc
Approximately one percent of users experience side effects from Synvisc. Most of these can quickly be handled and will fade in time. Typical side effects include mild pain, heat, swelling or redness around the injection site. Let your doctor understand if these side effects strike make sure that this condition does not require additional medical examination.

At 2 months’ follow-up, the PRP and thinner HA groups revealed a similar improvement, with better results compared to the high-molecular weight HA group (thicker HA). At 6 months’ follow-up, better results were observed in the PRP group. PRP and HA treatments provided comparable lead to patients 50 or older. The conclusion specifies that better results were seen in younger and more active patients who had a low degree of cartilage degeneration, whereas an even worse result was seen in more advanced knee arthritis joints and in older patients.

The outcome? PRP seems to work much better than HA and neither works well in patients with more severe arthritis. This fits with what we see in our Colorado clinic, with many of our effective knee stem cell patients already having actually failed PRP and HA. This likewise fits with other recent studies showing that PRP is much better than steroid shots for problems like plantar fascititis.

Synvisc or Euflexxa?

These are just two of a number of agents used in OA called viscosupplements which consist of hyaluronic acid. The medications you point out are injected directly into the knee joint once a week for 3 weeks. There are others that are five injections, and one that is a single injection. All are for treatment of pain in osteoarthritis in knee in patients who have failed nonpharmacologic treatment and easy analgesics. They are a lot alike that we would not recommend one over the other.

These injections work for some people but not all. Some individuals can experience a flare up of joint pain after the injection. If this occurs, you ought to contact your doctor.

Synvisc vs. Supartz: Similarities and Differences

Synvisc and Supartz are viscosupplementation medications. They are often used to treat osteoarthritis of the knee. Osteoarthritis, the most typical type of arthritis, damages cartilage in the joints. According to the American College of Rheumatology, roughly 27 million people in the United States have osteoarthritis. It is caused by recurring movement, wear and tear, and stress on the joints. Symptoms are most likely to appear after age 40.

Osteoarthritis causes pain and inflammation. It can restrict the range of movement in your joints. Arthritis in the knee can make it hard to stand, walk, or climb stairs, triggering a considerable impact on your quality of life. It’s a progressive condition, so symptoms normally intensify gradually.

There’s no cure, but there are a range of treatment choices that might help alleviate some symptoms. These include starting a workout routine, relieving stress on the joints, and dropping weight. Over the counter and prescription strength anti-inflammatory and pain relief medications may be helpful. Some patients take advantage of corticosteroid injections in the impacted joints. Complementary therapies such as massage and chiropractic adjustment can likewise be useful.


It might take several weeks and even a few months to feel the complete result. Each of these medications can provide approximately six months of symptom relief, minimizing pain and improving variety of movement. One has actually not been revealed to be significantly more effective than the other.

When it comes to the efficiency of viscosupplementation in general, research studies have had blended results. Some medical trials concluded that the procedure leads to very little benefit, together with an increased risk of side effects. Nevertheless, other trials have shown improved symptoms for approximately a year following the final injection. More studies are had to effectively gauge the efficiency of viscosupplementation.

Last modified: August 28, 2016


The Author

Reyus Mammadli

As a healthy lifestyle advisor I try to guide individuals in becoming more aware of living well and healthy through a series of proactive and preventive measures, disease prevention steps, recovery after illness or medical procedures.

Education: Bachelor Degree of Medical Equipment and Electronics.

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